Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | PRKDC | P78527 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.31 |
| ▸ | YTHDF2 | Q9Y5A9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12647317 | 0.81 | YTHDC1 (0.33) | PIK3CDPIK3CAPIK3CBPIK3CGPRKDC | |
| SCHEMBL8801 | 0.78 | PIK3CD (0.42) | PIK3CDPIK3CAPIK3CBPIK3CGPRKDC | |
| SCHEMBL13717500 | 0.77 | PDPK1 (0.44) | CHEK1YTHDC1YTHDF2 | |
| SCHEMBL311873 | 0.76 | CHEK1 (0.52) | CHEK1 | |
| SCHEMBL21620529 | 0.76 | CHEK1 (0.35) | CHEK1YTHDC1YTHDF2 | |
| SCHEMBL4565125 | 0.76 | CHEK1 (0.32) | CHEK1 | |
| SCHEMBL15473878 | 0.76 | YTHDC1 (0.31) | YTHDC1YTHDF2 | |
| SCHEMBL13717667 | 0.76 | CHEK1 (0.46) | CHEK1 | |
| SCHEMBL7247749 | 0.76 | ALDH1A1 (0.38) | — | |
| SCHEMBL12540861 | 0.76 | CYP1A2 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3345907-B1 | PYRAZOLO[3,4-D]PYRIMIDINE COMPOUNDS OR SALTS THEREOF | TAIHO PHARMACEUTICAL CO LTD (JP) | 2020-04-22 | — | — | EP | disclosed |
| EP-3345907-A1 | NOVEL PYRAZOLO[3,4-d]PYRIMIDINE COMPOUND OR SALT THEREOF | Taiho Pharmaceutical Co., Ltd. (JP) | 2018-07-11 | — | — | EP | disclosed |