Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.37 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.35 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.33 |
| ▸ | ECE1 | P42892 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11119411 | 1.00 | SLC22A6 (0.37) | SLC22A6GABRR1LMNACACNA2D1CACNB3 | |
| SCHEMBL13707889 | 0.85 | CACNA2D1 (0.36) | SLC22A6GABRR1LMNACACNA2D1CACNB3 | |
| SCHEMBL5144356 | 0.85 | ECE1 (0.45) | ECE1 | |
| SCHEMBL5430130 | 0.85 | ECE1 (0.45) | ECE1 | |
| SCHEMBL17772921 | 0.85 | CACNA2D1 (0.36) | SLC22A6GABRR1LMNACACNA2D1CACNB3 | |
| SCHEMBL2916475 | 0.83 | MME (0.44) | SLC22A6MMESMN1; SMN2 | |
| SCHEMBL3995863 | 0.83 | MME (0.44) | SLC22A6MMESMN1; SMN2 | |
| SCHEMBL7745087 | 0.80 | TGFBR1 (0.34) | SLC22A6GABRR1LMNACACNA2D1CACNB3 | |
| SCHEMBL4576097 | 0.78 | CA1 (0.34) | ECE1 | |
| SCHEMBL22215185 | 0.78 | CA1 (0.34) | ECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018127699-A1 | COMPOUNDS FOR TREATING CANCER | Bicyclerd Limited (GB) | 2018-07-12 | — | — | WO | disclosed |