Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.36 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.36 |
| ▸ | ECE1 | P42892 | 2/20 | 0.34 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.34 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.33 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GNPAT | O15228 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17772921 | 1.00 | CACNA2D1 (0.36) | CACNA2D1CACNB3CACNA1CPGRADRA1A | |
| SCHEMBL20375586 | 0.85 | SLC22A6 (0.37) | CACNA2D1CACNB3CACNA1CPGRADRA1A | |
| SCHEMBL22912327 | 0.85 | FFAR3 (0.36) | CACNA2D1CACNB3CACNA1CPGRADRA1A | |
| SCHEMBL11119411 | 0.85 | SLC22A6 (0.37) | CACNA2D1CACNB3CACNA1CPGRADRA1A | |
| SCHEMBL7351840 | 0.84 | ECE1 (0.46) | ECE1 | |
| SCHEMBL7351838 | 0.84 | ECE1 (0.46) | ECE1 | |
| SCHEMBL23764918 | 0.84 | FNTA (0.35) | CACNA2D1CACNB3CACNA1CPGRADRA1A | |
| SCHEMBL13233705 | 0.84 | FNTA (0.35) | CACNA2D1CACNB3CACNA1CPGRADRA1A | |
| SCHEMBL19729223 | 0.83 | ALDH1A1 (0.42) | ECE1 | |
| SCHEMBL14199849 | 0.82 | CA2 (0.42) | LMNAMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7595299-B2 | Peptides as NS3-serine protease inhibitors of hepatitis C virus | SCHERING CORPORATION (US) | 2009-09-29 | — | — | US | disclosed |
| US-7169760-B2 | Peptides as NS3-serine protease inhibitors of hepatitis C virus | SCHERING CORPORATION (US) | 2007-01-30 | — | — | US | disclosed |