Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20375537 | 0.88 | CYP3A4 (0.40) | RAB9ANPC1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL17802503 | 0.76 | RAB9A (0.49) | RAB9ANPC1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL17802442 | 0.69 | ABL1 (0.54) | RAB9ANPC1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL17802472 | 0.69 | NPC1 (0.52) | RAB9ANPC1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL17802478 | 0.69 | RAB9A (0.52) | RAB9ANPC1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL17802492 | 0.68 | CYP19A1 (0.52) | RAB9ANPC1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL17802455 | 0.67 | HSD17B10 (0.43) | RAB9ANPC1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL17802499 | 0.66 | NPC1 (0.49) | RAB9ANPC1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL17802497 | 0.64 | NPC1 (0.47) | RAB9ANPC1MEN1KMT2APIK3CA | |
| SCHEMBL17802462 | 0.64 | RAB9A (0.47) | RAB9ANPC1MAPTALDH1A1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3227302-B1 | BICYCLIC COMPOUNDS AS PEST CONTROLLERS | BAYER CROPSCIENCE AG (DE) | 2018-07-11 | — | — | EP | disclosed |