Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3A | P31941 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 6/20 | 0.32 |
| ▸ | DRD2 | P14416 | 5/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.32 |
| ▸ | HRH2 | P25021 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2454626 | 0.79 | APOBEC3A (0.46) | APOBEC3AAPOBEC3GHSD17B10MAPTGAA | |
| SCHEMBL2049076 | 0.79 | APOBEC3A (0.46) | APOBEC3AAPOBEC3GHSD17B10MAPTGAA | |
| SCHEMBL11244439 | 0.78 | APOBEC3A (0.44) | APOBEC3AAPOBEC3GHSD17B10MAPTGAA | |
| SCHEMBL2037902 | 0.78 | APOBEC3A (0.44) | APOBEC3AAPOBEC3GHSD17B10MAPTGAA | |
| Hydrochloric Acid SCHEMBL18918217 | 0.78 | APOBEC3A (0.44) | APOBEC3AAPOBEC3GHSD17B10MAPTGAA | |
| SCHEMBL28345406 | 0.75 | APOBEC3A (0.42) | APOBEC3AAPOBEC3GHSD17B10MAPTGAA | |
| SCHEMBL2043050 | 0.75 | APOBEC3A (0.42) | APOBEC3AAPOBEC3GHSD17B10MAPTGAA | |
| SCHEMBL2038639 | 0.74 | APOBEC3A (0.41) | APOBEC3AAPOBEC3GHSD17B10MAPTGAA | |
| SCHEMBL11972116 | 0.74 | APOBEC3A (0.41) | APOBEC3AAPOBEC3GHSD17B10MAPTGAA | |
| SCHEMBL7085659 | 0.74 | NOS1 (0.43) | APOBEC3AAPOBEC3GHSD17B10MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2507245-A2 | MULTICYCLIC COMPOUNDS AND METHODS OF USE THEREOF | Sunovion Pharmaceuticals Inc. (US) | 2012-10-10 | — | — | EP | disclosed |
| WO-2011069063-A2 | MULTICYCLIC COMPOUNDS AND METHODS OF USE THEREOF | SUNOVION PHARMACEUTICALS, INC. (US) | 2011-06-09 | — | — | WO | disclosed |