Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 4/20 | 0.43 |
| ▸ | NOS2 | P35228 | 4/20 | 0.43 |
| ▸ | DRD3 | P35462 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | DRD2 | P14416 | 4/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | HRH1 | P35367 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2043050 | 0.81 | APOBEC3A (0.42) | DRD3MAPTDRD2ADRA2ALMNA | |
| SCHEMBL2038639 | 0.80 | APOBEC3A (0.41) | DRD3MAPTDRD2ADRA2ALMNA | |
| SCHEMBL11972116 | 0.80 | APOBEC3A (0.41) | NOS1NOS2DRD3MAPTDRD2 | |
| SCHEMBL3536970 | 0.76 | NOS1 (0.33) | NOS1NOS2 | |
| SCHEMBL12644103 | 0.76 | APOBEC3A (0.38) | DRD3MAPTDRD2ADRA2AADRA2B | |
| SCHEMBL17609967 | 0.75 | DRD3 (0.38) | NOS1NOS2DRD3DRD2ADRA2A | |
| SCHEMBL11972364 | 0.75 | ADRB3 (0.37) | MAPTAPOBEC3AAPOBEC3GGAAHSD17B10 | |
| SCHEMBL2037898 | 0.74 | APOBEC3A (0.44) | DRD3MAPTDRD2ADRA2ALMNA | |
| SCHEMBL14906838 | 0.74 | APOBEC3A (0.36) | DRD3MAPTDRD2ADRA2AADRA2B | |
| Formic Acid SCHEMBL3542174 | 0.73 | NOS1 (0.31) | NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6770761-B2 | BROMINATION OF 1,4-CYCLOHEXANEDIONE BY BROMINE IN AN ALCOHOLIC SOLVENT; TREATMENT WITH THIOUREA OR N-ACYLTHIOUREA; ISOMERIZATION, CYCLIZATION; PRAMIPEXOLE SYNTHESIS | SYNTHON BV (NL) | 2004-08-03 | — | — | US | disclosed |
| US-20040029936-A1 | Process for preparation of 2-amino-6 (alkyl) amino-4,5,6,7-tetrahydrobenzothiazoles | SYNTHON IP INC. | 2004-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040029936-A1 | Process for preparation of 2-amino-6 (alkyl) amino-4,5,6,7-tetrahydrobenzothiazoles | PAH, HTR6, HTR4 | NOS1 1529/4885NOS2 1162/4885DRD3 676/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.