Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.70 |
| ▸ | TSHR | P16473 | 3/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.70 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.70 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.70 |
| ▸ | KDR | P35968 | 1/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 4/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.66 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.66 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.66 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.59 |
| ▸ | CA12 | O43570 | 2/20 | 0.59 |
| ▸ | CA1 | P00915 | 2/20 | 0.59 |
| ▸ | CA2 | P00918 | 2/20 | 0.59 |
| ▸ | CA7 | P43166 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propylparaben SCHEMBL429594 | 0.83 | ESR1 (1.00) | ESR1TSHRALDH1A1CHRM1SLC6A2 | |
| Propylparaben SCHEMBL977 | 0.83 | ESR1 (1.00) | ESR1TSHRALDH1A1CHRM1SLC6A2 | |
| SCHEMBL20380504 | 0.82 | RAB9A (0.48) | ESR1TSHRALDH1A1CHRM1SLC6A2 | |
| SCHEMBL15951668 | 0.82 | ESR1 (0.54) | ESR1TSHRALDH1A1CHRM1SLC6A2 | |
| Propylparaben SCHEMBL9406450 | 0.81 | ESR1 (0.96) | ESR1TSHRALDH1A1CHRM1SLC6A2 | |
| Propylparaben SCHEMBL1010568 | 0.81 | ESR1 (0.96) | ESR1TSHRALDH1A1CHRM1SLC6A2 | |
| Propylparaben SCHEMBL5671589 | 0.81 | ESR1 (0.96) | ESR1TSHRALDH1A1CHRM1SLC6A2 | |
| Propylparaben SCHEMBL37112 | 0.81 | ESR1 (0.96) | ESR1TSHRALDH1A1CHRM1SLC6A2 | |
| Propylparaben SCHEMBL6315856 | 0.81 | ESR1 (0.96) | ESR1TSHRALDH1A1CHRM1SLC6A2 | |
| Propylparaben SCHEMBL8779117 | 0.81 | ESR1 (0.96) | ESR1TSHRALDH1A1CHRM1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10023555-B2 | NSAIDs derivatives and uses thereof | RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (US) | 2018-07-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10023555-B2 | NSAIDs derivatives and uses thereof | PTGES, PTGES3, PTGS1 | ESR1 4383/4885TSHR 4747/4885ALDH1A1 383/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.