Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.45 |
| ▸ | RXRB | P28702 | 2/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.31 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.30 |
| ▸ | BCR | P11274 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | DHODH | Q02127 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26173346 | 0.97 | RXRA (0.48) | RXRARXRBESR1CNR2HSD17B1 | |
| SCHEMBL18308799 | 0.95 | RXRA (0.42) | RXRARXRBESR1CNR2DHODH | |
| SCHEMBL26173308 | 0.95 | RXRA (0.50) | RXRARXRBESR1CNR2HSD17B1 | |
| SCHEMBL18621840 | 0.89 | RXRA (0.42) | RXRARXRBESR1HSD17B1HSD17B2 | |
| SCHEMBL18308813 | 0.87 | RXRA (0.37) | RXRARXRBESR1CNR2HSD17B1 | |
| SCHEMBL18308782 | 0.85 | RXRA (0.36) | RXRARXRBCNR2 | |
| SCHEMBL18806016 | 0.84 | RXRA (0.35) | RXRARXRBCNR2 | |
| SCHEMBL18806011 | 0.82 | RXRA (0.34) | RXRARXRBCNR2 | |
| SCHEMBL18308776 | 0.81 | RXRA (0.35) | RXRARXRBCNR2 | |
| SCHEMBL1687651 | 0.80 | ACHE (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180201837-A1 | Method of Reducing ODF Mura in Polymer Stabilised Liquid Crystal Displays | MERCK PATENT GMBH (DE) | 2018-07-19 | — | — | US | disclosed |