Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 20/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2037381 | 0.88 | PDE10A (0.62) | PDE10A | |
| SCHEMBL2040370 | 0.87 | PDE10A (0.63) | PDE10A | |
| SCHEMBL2053605 | 0.84 | PDE10A (0.58) | PDE10A | |
| SCHEMBL2036380 | 0.83 | PDE10A (0.58) | PDE10A | |
| SCHEMBL2043214 | 0.83 | PDE10A (0.50) | PDE10A | |
| SCHEMBL2053542 | 0.82 | PDE10A (0.59) | PDE10A | |
| SCHEMBL2038211 | 0.77 | PDE10A (0.56) | PDE10A | |
| SCHEMBL2044837 | 0.74 | PDE10A (0.52) | PDE10A | |
| SCHEMBL2053347 | 0.72 | PDE10A (0.58) | PDE10A | |
| SCHEMBL2040125 | 0.71 | PDE10A (0.61) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011072695-A1 | PHENYLIMIDAZOLE DERIVATIVES COMPRISING AN ETHYNYLENE LINKER AS PDE10A ENZYME INHIBITORS | H. LUNDBECK A/S (DK) | 2011-06-23 | — | — | WO | disclosed |