Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 20/20 | 0.55 |
| ▸ | CTSK | P43235 | 10/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17474633 | 0.88 | CTSC (0.70) | CTSCCTSK | |
| SCHEMBL17477214 | 0.77 | CTSC (0.48) | CTSCCTSK | |
| SCHEMBL17483558 | 0.71 | CTSC (0.64) | CTSCCTSK | |
| SCHEMBL31704121 | 0.71 | CTSC (1.00) | CTSCCTSK | |
| SCHEMBL21172962 | 0.71 | CTSC (1.00) | CTSCCTSK | |
| SCHEMBL17584779 | 0.71 | CTSC (1.00) | CTSCCTSK | |
| SCHEMBL17483511 | 0.71 | CTSC (0.49) | CTSCCTSK | |
| SCHEMBL17485376 | 0.69 | RORC (0.42) | CTSCCTSK | |
| SCHEMBL16092767 | 0.68 | CTSC (0.56) | CTSCCTSK | |
| SCHEMBL17474629 | 0.67 | CTSC (0.90) | CTSCCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3174879-B1 | SUBSTITUTED OXETANES AND THEIR USE AS INHIBITORS OF CATHEPSIN C | BOEHRINGER INGELHEIM INT (DE) | 2018-07-18 | — | — | EP | disclosed |