Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 18/20 | 0.49 |
| ▸ | CTSK | P43235 | 10/20 | 0.49 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.37 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17483513 | 0.88 | CTSC (0.45) | CTSCCTSK | |
| SCHEMBL17485376 | 0.78 | RORC (0.42) | CTSCCTSKALKKITKDR | |
| SCHEMBL20384054 | 0.78 | CTSC (0.57) | CTSCCTSK | |
| SCHEMBL24981840 | 0.76 | CTSC (0.52) | CTSCCTSKALK | |
| SCHEMBL28989271 | 0.76 | CTSC (0.52) | CTSCCTSKALK | |
| SCHEMBL24374736 | 0.74 | LGMN (0.42) | ALKKITKDR | |
| SCHEMBL17586446 | 0.74 | CTSC (0.64) | CTSCCTSK | |
| SCHEMBL17474633 | 0.73 | CTSC (0.70) | CTSCCTSK | |
| SCHEMBL31757930 | 0.72 | CTSC (0.40) | CTSCCTSK | |
| SCHEMBL17474629 | 0.72 | CTSC (0.90) | CTSCCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3174879-B1 | SUBSTITUTED OXETANES AND THEIR USE AS INHIBITORS OF CATHEPSIN C | BOEHRINGER INGELHEIM INT (DE) | 2018-07-18 | — | — | EP | disclosed |
| US-9440960-B2 | Substituted oxetanes and their use as inhibitors of cathepsin C | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2016-09-13 | — | — | US | disclosed |
| US-20160031861-A1 | SUBSTITUTED OXETANES AND THEIR USE AS INHIBITORS OF CATHEPSIN C | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2016-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160031861-A1 | SUBSTITUTED OXETANES AND THEIR USE AS INHIBITORS OF CATHEPSIN C | CTSE, CTSC, CTSZ | CTSC 2/4885CTSK 10/4885ALK 3303/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.