Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 16/20 | 0.54 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15069384 | 0.90 | BRD4 (0.54) | BRD4 | |
| SCHEMBL20384519 | 0.90 | BRD4 (0.56) | BRD4 | |
| SCHEMBL15069411 | 0.88 | BRD4 (0.55) | BRD4 | |
| SCHEMBL31395498 | 0.88 | BRD4 (0.55) | BRD4 | |
| SCHEMBL20384392 | 0.88 | BRD4 (0.54) | BRD4 | |
| SCHEMBL20384194 | 0.86 | BRD4 (0.54) | BRD4 | |
| SCHEMBL15069180 | 0.84 | BRD4 (0.49) | BRD4 | |
| SCHEMBL15069163 | 0.83 | BRD4 (0.52) | BRD4HTR6 | |
| SCHEMBL30324901 | 0.83 | BRD4 (0.52) | BRD4HTR6 | |
| SCHEMBL31395353 | 0.80 | BRD4 (0.55) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018130174-A1 | PYRROLO[2,3-C]PYRIDINE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF IN MEDICINE | 江苏豪森药业集团有限公司 | 2018-07-19 | — | — | WO | disclosed |