SCHEMBL2038457

SCHEMBL2038457

COC(=O)C1CCC(c2ccccc2Cl)N1C(=O)c1ccccc1-c1ccccc1C(=N)N

nearest known ligand 0.50

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FFAR2 O15552 20/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2034159 1.00 FFAR2 (0.50) FFAR2
SCHEMBL2040966 0.88 FFAR2 (0.49) FFAR2
SCHEMBL29788298 0.88 FFAR2 (0.49) FFAR2
SCHEMBL31047156 0.80 FFAR2 (0.63) FFAR2
SCHEMBL14635348 0.80 FFAR2 (0.63) FFAR2
SCHEMBL2037011 0.80 FFAR2 (0.63) FFAR2
SCHEMBL24102467 0.79 FFAR2 (0.55) FFAR2
SCHEMBL24102463 0.79 FFAR2 (0.55) FFAR2
SCHEMBL2038951 0.79 FFAR2 (0.60) FFAR2
SCHEMBL29788098 0.79 FFAR2 (0.60) FFAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2513053-A1 PYRROLIDINE OR THIAZOLIDINE CARBOXYLIC ACID DERIVATIVES, PHARMACEUTICAL COMPOSITION AND METHODS FOR USE IN TREATING METABOLIC DISORDERSAS AS AGONISTS OF G- PROTEIN COUPLED RECEPTOR 43 (GPR43) Euroscreen S.A. (BE) 2012-10-24 EP disclosed
WO-2011073376-A1 PYRROLIDINE OR THIAZOLIDINE CARBOXYLIC ACID DERIVATIVES, PHARMACEUTICAL COMPOSITION AND METHODS FOR USE IN TREATING METABOLIC DISORDERSAS AS AGONISTS OF G- PROTEIN COUPLED RECEPTOR 43 (GPR43) EUROSCREEN S.A. (BE) 2011-06-23 WO disclosed