SCHEMBL24102467

SCHEMBL24102467

COC(=O)C1CCC(c2ccccc2Cl)N1C(C)=O

nearest known ligand 0.55

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FFAR2 O15552 20/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24102463 1.00 FFAR2 (0.55) FFAR2
SCHEMBL2037101 0.81 FFAR2 (0.69) FFAR2
SCHEMBL21313730 0.81 FFAR2 (0.69) FFAR2
SCHEMBL29787773 0.81 FFAR2 (0.69) FFAR2
SCHEMBL14635350 0.81 FFAR2 (0.69) FFAR2
SCHEMBL26040758 0.80 FFAR2 (0.49) FFAR2
SCHEMBL21313770 0.79 FFAR2 (0.83) FFAR2
SCHEMBL2038457 0.79 FFAR2 (0.50) FFAR2
SCHEMBL24101925 0.79 FFAR2 (0.83) FFAR2
SCHEMBL21313769 0.79 FFAR2 (0.83) FFAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021250174-A1 SYNTHESIS OF (2S,5R)-5-(2-CHLOROPHENYL)-1-(2'-METHOXY-[1,1'-BIPHENYL]-4-CARBONYL)PYRROLIDINE-2-CARBOXYLIC ACID EPICS THERAPEUTICS (BE) 2021-12-16 WO disclosed