Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | PHGDH | O43175 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | POLQ | O75417 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19943326 | 0.85 | POLB (0.38) | FAAHPHGDHMGLLCA12CA1 | |
| SCHEMBL19174613 | 0.80 | FAAH (0.44) | FAAHPHGDHMGLLCA12CA1 | |
| SCHEMBL22068900 | 0.79 | ALDH1A1 (0.35) | L3MBTL1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL19866402 | 0.75 | MAPT (0.33) | L3MBTL1KDM4EALDH1A1MAPT | |
| SCHEMBL18436868 | 0.74 | FAAH (0.39) | FAAHPHGDHMGLLCA12CA1 | |
| SCHEMBL19193232 | 0.72 | FAAH (0.38) | FAAHPHGDHMGLLCA12CA1 | |
| SCHEMBL22503861 | 0.70 | FAAH (0.36) | FAAHPHGDHMGLLCA12CA1 | |
| SCHEMBL20859796 | 0.70 | NR1H4 (0.36) | LMNAL3MBTL1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL19831560 | 0.67 | MAOB (0.33) | CA12CA1CA9LMNAPOLB | |
| SCHEMBL11145953 | 0.66 | FAAH (0.50) | FAAHPHGDHMGLLCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2252624-B1 | ELECTROLUMINESCENT METAL COMPLEXES WITH DIBENZO[F,H]QUINOXALINES | UDC IRELAND LTD (IE) | 2018-07-18 | — | — | EP | disclosed |