SCHEMBL20385183

SCHEMBL20385183

CC(C)n1cnc2ccc(CC(C)n3cnc4ncccc43)cc21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 7/20 0.38
NPC1 O15118 6/20 0.38
KDM4E B2RXH2 5/20 0.38
ALDH1A1 P00352 4/20 0.38
SMN1; SMN2 Q16637 4/20 0.38
GAA P10253 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
HIF1A Q16665 1/20 0.36
HPGD P15428 3/20 0.35
HSD17B10 Q99714 2/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
HCAR3 P49019 1/20 0.34
MAPT P10636 3/20 0.34
TP53 P04637 2/20 0.34
GFER P55789 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
IDE P14735 1/20 0.33
BRD4 O60885 1/20 0.33
LTA4H P09960 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1106477 0.79 HIF1A (0.45) RAB9ANPC1KDM4EALDH1A1SMN1; SMN2
SCHEMBL20664871 0.73 HIF1A (0.44) RAB9ANPC1KDM4EALDH1A1SMN1; SMN2
SCHEMBL20946383 0.72 RAB9A (0.46) RAB9ANPC1KDM4EALDH1A1SMN1; SMN2
SCHEMBL19422782 0.70 MEN1 (0.41) RAB9ANPC1KDM4EALDH1A1SMN1; SMN2
SCHEMBL21311331 0.69 MEN1 (0.46) RAB9ANPC1KDM4EALDH1A1SMN1; SMN2
SCHEMBL22606405 0.68 HIF1A (0.43) HIF1A
SCHEMBL23760241 0.67 HIF1A (0.43) RAB9ANPC1KDM4EALDH1A1SMN1; SMN2
SCHEMBL23949542 0.67 RAB9A (0.56) RAB9ANPC1KDM4EALDH1A1SMN1; SMN2
SCHEMBL1027011 0.66 HPGD (0.68) RAB9ANPC1KDM4EALDH1A1SMN1; SMN2
SCHEMBL7732282 0.65 RAB9A (0.50) RAB9ANPC1KDM4EALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180205023-A1 Delayed Fluorescence Compound, and Organic Light Emitting Diode and Display Device Using the Same LG DISPLAY CO., LTD. (KR) 2018-07-19 US disclosed