Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | GLP1R | P43220 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.36 |
| ▸ | FABP4 | P15090 | 1/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20385441 | 0.80 | HPGD (0.46) | HDAC8MEN1HPGDKMT2AHSD17B10 | |
| SCHEMBL20385245 | 0.75 | BRD4 (0.40) | HDAC8MEN1HPGDKMT2AHSD17B10 | |
| SCHEMBL15826415 | 0.75 | GLP1R (0.47) | MEN1HPGDKMT2AHSD17B10GLP1R | |
| SCHEMBL20385368 | 0.75 | MEN1 (0.44) | MEN1HPGDKMT2AHSD17B10GLP1R | |
| SCHEMBL15333219 | 0.72 | CYP11B1 (0.66) | CYP11B1CYP11B2TNFLMNAHTT | |
| SCHEMBL19836338 | 0.70 | GLP1R (0.53) | MEN1HPGDKMT2AHSD17B10GLP1R | |
| SCHEMBL29734901 | 0.70 | GLP1R (0.47) | MEN1HPGDKMT2AHSD17B10GLP1R | |
| SCHEMBL29612495 | 0.70 | GLP1R (0.53) | MEN1HPGDKMT2AHSD17B10GLP1R | |
| SCHEMBL18009808 | 0.70 | GLP1R (0.47) | MEN1HPGDKMT2AHSD17B10GLP1R | |
| SCHEMBL12421824 | 0.69 | LCK (0.45) | MEN1HPGDKMT2AHSD17B10CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018130227-A1 | AROMATIC RING-CONTAINING COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION, AND USE | 山东罗欣药业集团股份有限公司 | 2018-07-19 | — | — | WO | disclosed |