Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | GLP1R | P43220 | 1/20 | 0.43 |
| ▸ | FABP4 | P15090 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | NPM1 | P06748 | 1/20 | 0.39 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20259965 | 0.83 | HPGD (0.47) | HPGDMEN1KMT2AHSD17B10MAPK1 | |
| SCHEMBL20385368 | 0.81 | MEN1 (0.44) | HPGDMEN1KMT2AHSD17B10GLP1R | |
| SCHEMBL15826415 | 0.81 | GLP1R (0.47) | HPGDMEN1KMT2AHSD17B10GLP1R | |
| SCHEMBL20259966 | 0.81 | MEN1 (0.50) | HPGDMEN1KMT2AHSD17B10MAPK1 | |
| SCHEMBL20385274 | 0.81 | GLP1R (0.41) | HPGDMEN1KMT2AHSD17B10GLP1R | |
| SCHEMBL20385355 | 0.80 | HDAC8 (0.43) | HPGDMEN1KMT2AHSD17B10GLP1R | |
| SCHEMBL5865198 | 0.80 | MEN1 (0.69) | HPGDMEN1KMT2AHSD17B10MAPK1 | |
| SCHEMBL12788834 | 0.80 | PTGS2 (0.46) | MEN1KMT2ALMNAMAPTPTGS2 | |
| SCHEMBL29734901 | 0.77 | GLP1R (0.47) | HPGDMEN1KMT2AHSD17B10GLP1R | |
| SCHEMBL19836338 | 0.77 | GLP1R (0.53) | HPGDMEN1KMT2AHSD17B10GLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018130227-A1 | AROMATIC RING-CONTAINING COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION, AND USE | 山东罗欣药业集团股份有限公司 | 2018-07-19 | — | — | WO | disclosed |