Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 1/20 | 0.53 |
| ▸ | FABP4 | P15090 | 2/20 | 0.47 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 6/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | CDK1 | P06493 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19836338 | 1.00 | GLP1R (0.53) | GLP1RFABP4HCAR3HPGDMEN1 | |
| SCHEMBL30847375 | 0.86 | HCAR3 (0.58) | GLP1RFABP4HCAR3HPGDMEN1 | |
| SCHEMBL7726925 | 0.86 | HCAR3 (0.58) | GLP1RFABP4HCAR3HPGDMEN1 | |
| SCHEMBL18009808 | 0.82 | GLP1R (0.47) | GLP1RFABP4HPGDMEN1KMT2A | |
| SCHEMBL29734901 | 0.82 | GLP1R (0.47) | GLP1RFABP4HPGDMEN1KMT2A | |
| SCHEMBL22272322 | 0.80 | HCAR3 (0.47) | GLP1RHCAR3HPGDMEN1KMT2A | |
| SCHEMBL7732282 | 0.80 | RAB9A (0.50) | GLP1RHCAR3HPGDMEN1KMT2A | |
| SCHEMBL29037886 | 0.79 | GLP1R (0.45) | GLP1RFABP4HPGDMEN1KMT2A | |
| SCHEMBL23063551 | 0.79 | HCAR3 (0.50) | GLP1RHCAR3HPGDMEN1KMT2A | |
| SCHEMBL7726920 | 0.79 | HCAR3 (0.46) | GLP1RHCAR3HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118724899-A | 2 (1H) -quinoxalinone compounds, pharmaceutical compositions and uses thereof | 中国药科大学 | 2024-10-01 | — | — | CN | disclosed |
| WO-2024044757-A1 | AMINOPYRIMIDINE AND AMINOTRIAZINE DERIVATIVES AS MYC PROTEIN MODULATORS | Sanford Burnham Prebys Medical Discovery Institute (US) | 2024-02-29 | — | — | WO | disclosed |
| CN-113382991-B | Aminopyrimidines useful for inhibiting protein tyrosine kinase activity | 深圳市塔吉瑞生物医药有限公司 | 2022-12-27 | — | — | CN | disclosed |
| CN-114430743-A | Thyroid hormone receptor beta agonist compounds | 拓臻制药公司 | 2022-05-03 | — | — | CN | disclosed |