Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 6/20 | 0.64 |
| ▸ | NFE2L2 | Q16236 | 6/20 | 0.64 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.63 |
| ▸ | USP2 | O75604 | 7/20 | 0.63 |
| ▸ | MEN1 | O00255 | 7/20 | 0.63 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.63 |
| ▸ | ATM | Q13315 | 3/20 | 0.63 |
| ▸ | HTR1A | P08908 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | THRB | P10828 | 2/20 | 0.53 |
| ▸ | APAF1 | O14727 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | HEXA | P06865 | 2/20 | 0.50 |
| ▸ | HEXB | P07686 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29086656 | 0.87 | HEXA (0.67) | KEAP1NFE2L2TLR9KMT2AUSP2 | |
| SCHEMBL10690064 | 0.86 | KEAP1 (0.64) | KEAP1NFE2L2TLR9KMT2AUSP2 | |
| SCHEMBL13964867 | 0.86 | KMT2A (0.67) | KEAP1NFE2L2TLR9KMT2AUSP2 | |
| SCHEMBL12023617 | 0.85 | KMT2A (0.70) | KEAP1NFE2L2TLR9KMT2AUSP2 | |
| SCHEMBL7646893 | 0.85 | KMT2A (0.70) | KEAP1NFE2L2TLR9KMT2AUSP2 | |
| SCHEMBL3891083 | 0.84 | KMT2A (0.74) | KEAP1NFE2L2TLR9KMT2AUSP2 | |
| SCHEMBL13964866 | 0.82 | USP2 (0.70) | KEAP1NFE2L2TLR9KMT2AUSP2 | |
| SCHEMBL9437193 | 0.81 | KMT2A (0.78) | KEAP1NFE2L2TLR9KMT2AUSP2 | |
| SCHEMBL20385847 | 0.81 | KEAP1 (0.61) | KEAP1NFE2L2TLR9KMT2AUSP2 | |
| SCHEMBL16224764 | 0.81 | KMT2A (0.73) | KEAP1NFE2L2TLR9KMT2AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3763371-A1 | METHODS OF ACUTE RESTORATION OF VASCULAR COMPLIANCE | Alumend, LLC (US) | 2021-01-13 | — | — | EP | disclosed |
| EP-3348555-A2 | COMPOSITIONS AND METHODS OF USING THE COMPOSITIONS FOR PLAQUE SOFTENING | Alumend, LLC (US) | 2018-07-18 | — | — | EP | disclosed |