Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.70 |
| ▸ | MEN1 | O00255 | 6/20 | 0.70 |
| ▸ | USP2 | O75604 | 5/20 | 0.70 |
| ▸ | KEAP1 | Q14145 | 4/20 | 0.70 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.70 |
| ▸ | ATM | Q13315 | 3/20 | 0.70 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.70 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | APAF1 | O14727 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 3/20 | 0.58 |
| ▸ | RGS12 | O14924 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12023617 | 1.00 | KMT2A (0.70) | KMT2AMEN1USP2KEAP1NFE2L2 | |
| SCHEMBL3891083 | 0.94 | KMT2A (0.74) | KMT2AMEN1USP2KEAP1NFE2L2 | |
| SCHEMBL7647662 | 0.91 | MEN1 (0.58) | KMT2AMEN1USP2KEAP1NFE2L2 | |
| SCHEMBL9437193 | 0.89 | KMT2A (0.78) | KMT2AMEN1USP2KEAP1NFE2L2 | |
| SCHEMBL20735101 | 0.87 | MEN1 (0.62) | KMT2AMEN1USP2KEAP1NFE2L2 | |
| SCHEMBL29086656 | 0.86 | HEXA (0.67) | KMT2AMEN1USP2KEAP1NFE2L2 | |
| SCHEMBL10690064 | 0.85 | KEAP1 (0.64) | KMT2AMEN1USP2KEAP1NFE2L2 | |
| SCHEMBL20385751 | 0.85 | KEAP1 (0.64) | KMT2AMEN1USP2KEAP1NFE2L2 | |
| SCHEMBL20735100 | 0.85 | MEN1 (0.60) | KMT2AMEN1USP2KEAP1NFE2L2 | |
| SCHEMBL13964867 | 0.85 | KMT2A (0.67) | KMT2AMEN1USP2KEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6486319-B1 | Thermochromic rylene dyes | BASF AKTIENGESELLSCHAFT (DE) | 2002-11-26 | — | — | US | disclosed |