Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY2 | P41231 | 2/20 | 0.32 |
| ▸ | POLG | P54098 | 1/20 | 0.32 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.31 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | POLA1 | P09884 | 1/20 | 0.30 |
| ▸ | POLD1 | P28340 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20383456 | 1.00 | P2RY2 (0.32) | P2RY2POLGP2RY4P2RY6POLB | |
| SCHEMBL20021614 | 1.00 | P2RY2 (0.32) | P2RY2POLGP2RY4P2RY6POLB | |
| SCHEMBL14820564 | 1.00 | P2RY2 (0.32) | P2RY2POLGP2RY4P2RY6POLB | |
| SCHEMBL14806824 | 1.00 | P2RY2 (0.32) | P2RY2POLGP2RY4P2RY6POLB | |
| SCHEMBL20387895 | 0.96 | P2RY2 (0.32) | P2RY2POLGP2RY4P2RY6 | |
| SCHEMBL19569898 | 0.96 | P2RY2 (0.32) | P2RY2POLGP2RY4P2RY6 | |
| SCHEMBL20329770 | 0.95 | P2RY2 (0.33) | P2RY2POLGP2RY4P2RY6POLB | |
| SCHEMBL14392447 | 0.95 | P2RY2 (0.32) | P2RY2POLGP2RY4P2RY6 | |
| SCHEMBL20821471 | 0.94 | P2RY2 (0.32) | P2RY2P2RY4P2RY6 | |
| SCHEMBL17227493 | 0.94 | P2RY2 (0.32) | P2RY2P2RY4P2RY6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11858923-B2 | Secondary amine-substituted coumarin compounds and their uses as fluorescent labels | ILLUMINA CAMBRIDGE LIMITED (GB) | 2024-01-02 | — | — | US | disclosed |
| US-20230025669-A1 | SECONDARY AMINE-SUBSTITUTED COUMARIN COMPOUNDS AND THEIR USES AS FLUORESCENT LABELS | ILLUMINA CAMBRIDGE LIMITED (GB) | 2023-01-26 | — | — | US | disclosed |
| US-20230022437-A1 | EXOCYCLIC AMINE SUBSTITUTED COUMARIN COMPOUNDS AND USES AS FLUORESCENT LABELS | ILLUMINA CAMBRIDGE LIMITED (GB) | 2023-01-26 | — | — | US | disclosed |
| US-20220049292-A1 | MULTIPLEXED FLUORESCENT DETECTION OF ANALYTES | ILLUMINA CAMBRIDGE LIMITED (GB) | 2022-02-17 | — | — | US | disclosed |
| US-20210188832-A1 | SECONDARY AMINE-SUBSTITUTED COUMARIN COMPOUNDS AND THEIR USES AS FLUORESCENT LABELS | ILLUMINA CAMBRIDGE LIMITED (GB) | 2021-06-24 | — | — | US | disclosed |
| US-10907196-B2 | Coumarin compounds and their uses as fluorescent labels | ILLUMINA CAMBRIDGE LIMITED (GB) | 2021-02-02 | — | — | US | disclosed |
| US-20200277529-A1 | EXOCYCLIC AMINE SUBSTITUTED COUMARIN COMPOUNDS AND USES AS FLUORESCENT LABELS | ILLUMINA CAMBRIDGE LIMITED (GB) | 2020-09-03 | — | — | US | disclosed |
| US-20200277670-A1 | TERTIARY AMINE SUBSTITUTED COUMARIN COMPOUNDS AND USES AS FLUORESCENT LABELS | ILLUMINA CAMBRIDGE LIMITED (GB) | 2020-09-03 | — | — | US | disclosed |
| US-20200216882-A1 | COUMARIN COMPOUNDS AND THEIR USES AS FLUORESCENT LABELS | ILLUMINA CAMBRIDGE LIMITED (GB) | 2020-07-09 | — | — | US | disclosed |
| US-20190185918-A1 | COUMARIN COMPOUNDS AND THEIR USES AS FLUORESCENT LABELS | ILLUMINA CAMBRIDGE LIMITED (GB) | 2019-06-20 | — | — | US | disclosed |
| US-20180201981-A1 | COUMARIN COMPOUNDS AND THEIR USES AS FLUORESCENT LABELS | ILLUMINA CAMBRIDGE LIMITED (GB) | 2018-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190185918-A1 | COUMARIN COMPOUNDS AND THEIR USES AS FLUORESCENT LABELS | FBL, PHAX, DUT | P2RY2 1838/4885POLG 1318/4885P2RY4 825/4885 |
| US-20180201981-A1 | COUMARIN COMPOUNDS AND THEIR USES AS FLUORESCENT LABELS | FBL, PHAX, DUT | P2RY2 1838/4885POLG 1318/4885P2RY4 825/4885 |
| US-10907196-B2 | Coumarin compounds and their uses as fluorescent labels | FBL, PHAX, DUT | P2RY2 1838/4885POLG 1318/4885P2RY4 825/4885 |
| US-11858923-B2 | Secondary amine-substituted coumarin compounds and their uses as fluorescent labels | FBL, NSUN2, DNA2 | P2RY2 1845/4885POLG 828/4885P2RY4 1402/4885 |
| US-20200216882-A1 | COUMARIN COMPOUNDS AND THEIR USES AS FLUORESCENT LABELS | FBL, PHAX, DUT | P2RY2 1838/4885POLG 1318/4885P2RY4 825/4885 |
| US-20230025669-A1 | SECONDARY AMINE-SUBSTITUTED COUMARIN COMPOUNDS AND THEIR USES AS FLUORESCENT LABELS | FBL, NSUN2, DNA2 | P2RY2 1845/4885POLG 828/4885P2RY4 1402/4885 |
| US-20200277670-A1 | TERTIARY AMINE SUBSTITUTED COUMARIN COMPOUNDS AND USES AS FLUORESCENT LABELS | FBL, NAT10, DNMT3A | P2RY2 2633/4885POLG 1027/4885P2RY4 1196/4885 |
| US-20210188832-A1 | SECONDARY AMINE-SUBSTITUTED COUMARIN COMPOUNDS AND THEIR USES AS FLUORESCENT LABELS | FBL, NSUN2, DNA2 | P2RY2 1845/4885POLG 828/4885P2RY4 1402/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.