Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | CCR3 | P51677 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 3/20 | 0.40 |
| ▸ | ACHE | P22303 | 3/20 | 0.40 |
| ▸ | BACE1 | P56817 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL186185 | 0.78 | LOXL2 (0.44) | CNR2CNR1MEN1KMT2A | |
| SCHEMBL185133 | 0.74 | CNR2 (0.41) | CNR2CNR1RAB9A | |
| SCHEMBL19418435 | 0.74 | MAPK10 (0.47) | CNR2 | |
| SCHEMBL13159687 | 0.74 | MAPK10 (0.47) | CNR2 | |
| SCHEMBL1239998 | 0.73 | BCHE (0.61) | CCR3BCHEACHEBACE1MEN1 | |
| SCHEMBL184742 | 0.72 | CYP3A4 (0.40) | CNR2CNR1RAB9A | |
| SCHEMBL5556152 | 0.69 | BCHE (0.64) | BCHEACHEBACE1MEN1KMT2A | |
| SCHEMBL10073807 | 0.68 | MEN1 (0.69) | BCHEACHEBACE1MEN1KMT2A | |
| SCHEMBL23124775 | 0.68 | MEN1 (0.41) | BCHEACHEBACE1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL218521 | 0.68 | BCHE (0.62) | BCHEACHEBACE1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401256-A1 | COMPOUNDS AS BRADYKININ B1 ANTAGONISTS | Boehringer Ingelheim International GmbH (DE) | 2012-01-04 | — | — | EP | disclosed |
| WO-2010097372-A1 | COMPOUNDS AS BRADYKININ B1 ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-02 | — | — | WO | disclosed |