Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 4/20 | 0.32 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23603848 | 0.82 | KDM1A (0.35) | ALDH1A1KDM1A | |
| SCHEMBL23802683 | 0.78 | MEN1 (0.30) | — | |
| SCHEMBL13701281 | 0.76 | KDM1A (0.33) | ALDH1A1KDM1AKDM1B | |
| SCHEMBL10561767 | 0.74 | HPGD (0.33) | — | |
| SCHEMBL509469 | 0.74 | KDM1A (0.53) | ALDH1A1KDM1AKDM1B | |
| SCHEMBL20388691 | 0.74 | — | — | |
| SCHEMBL30409263 | 0.74 | KDM1A (0.53) | ALDH1A1KDM1AKDM1B | |
| SCHEMBL30034644 | 0.74 | KDM1A (0.30) | KDM1AKDM1B | |
| SCHEMBL23802694 | 0.74 | KDM1A (0.30) | KDM1AKDM1B | |
| SCHEMBL24834540 | 0.73 | CYP11B1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108329311-B | Tricyclic compound as selective estrogen receptor down-regulator and application thereof | 南京圣和药业股份有限公司 | 2022-02-22 | — | — | CN | disclosed |
| WO-2018130124-A1 | TRICYCLIC COMPOUND AS SELECTIVE ESTROGEN RECEPTOR DOWN-REGULATOR AND USE THEREOF | 南京圣和药业股份有限公司 | 2018-07-19 | — | — | WO | disclosed |