SCHEMBL13701281

SCHEMBL13701281

Fc1cc(Br)cc(F)c1[C@H]1CO1

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 4/20 0.33
KDM1B Q8NB78 1/20 0.33
ALDH1A1 P00352 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7783873 0.81 TSHR (0.36) TSHR
SCHEMBL7779153 0.81 TSHR (0.32) TSHR
SCHEMBL17865231 0.77 TSHR (0.30) TSHR
SCHEMBL23652657 0.76 TSHR (0.32) TSHR
SCHEMBL20388652 0.76 ALDH1A1 (0.33) KDM1AKDM1BALDH1A1
SCHEMBL578752 0.74 HTR1A (0.46)
SCHEMBL12685502 0.72
SCHEMBL12609570 0.72 KDM1A (0.55) KDM1AKDM1BALDH1A1
SCHEMBL12609563 0.72 KDM1A (0.55) KDM1AKDM1BALDH1A1
SCHEMBL19729052 0.72 EIF4A3 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2103589-A1 Polypenylenes as liquid crystals Merck Patent GmbH (DE) 2009-09-23 EP disclosed