Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29725088 | 0.94 | CYP1A2 (0.43) | CYP1A2SIGMAR1 | |
| SCHEMBL29725093 | 0.82 | CYP1A2 (0.50) | CYP1A2SIGMAR1 | |
| SCHEMBL9210867 | 0.81 | CYP1A2 (0.44) | CYP1A2SIGMAR1 | |
| SCHEMBL29401544 | 0.77 | CYP1A2 (0.41) | CYP1A2SIGMAR1 | |
| SCHEMBL29766202 | 0.72 | SIGMAR1 (0.36) | CYP1A2SIGMAR1 | |
| SCHEMBL22507922 | 0.70 | EPHX1 (0.38) | CYP1A2SIGMAR1 | |
| SCHEMBL10580160 | 0.69 | — | — | |
| SCHEMBL26256340 | 0.69 | SIGMAR1 (0.39) | CYP1A2SIGMAR1 | |
| SCHEMBL24127642 | 0.67 | CYP1A2 (0.44) | CYP1A2SIGMAR1 | |
| SCHEMBL29568023 | 0.67 | SIGMAR1 (0.42) | CYP1A2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2888255-B1 | HETEROCYCLIC MODULATORS OF HIF ACTIVITY FOR TREATMENT OF DISEASE | UNIV TEXAS (US) | 2018-07-18 | — | — | EP | disclosed |