Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 11/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | GNAI3 | P08754 | 3/20 | 0.37 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.37 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29725093 | 0.91 | CYP1A2 (0.50) | CYP1A2SIGMAR1NAAAEPHX1EPHX2 | |
| SCHEMBL29725088 | 0.83 | CYP1A2 (0.43) | CYP1A2SIGMAR1EPHX1 | |
| SCHEMBL20389488 | 0.81 | CYP1A2 (0.35) | CYP1A2SIGMAR1 | |
| SCHEMBL22507922 | 0.81 | EPHX1 (0.38) | CYP1A2SIGMAR1NAAAEPHX1EPHX2 | |
| SCHEMBL9213729 | 0.79 | CYP1A2 (0.55) | CYP1A2SIGMAR1NAAAEPHX1EPHX2 | |
| SCHEMBL29401544 | 0.75 | CYP1A2 (0.41) | CYP1A2SIGMAR1EPHX1 | |
| SCHEMBL10589508 | 0.72 | EPHX1 (0.52) | EPHX1 | |
| SCHEMBL3369909 | 0.72 | EPHX1 (0.52) | EPHX1 | |
| SCHEMBL3373268 | 0.72 | EPHX1 (0.52) | EPHX1 | |
| SCHEMBL37783 | 0.72 | EPHX1 (0.52) | EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0421441-B1 | Pantothenic acid derivatives | FUJIREBIO KK (JP) | 1995-01-25 | — | — | EP | disclosed |
| US-5120738-A | Cardiovascular disorders | FUJIREBIO INC. (JP) | 1992-06-09 | — | — | US | disclosed |
| EP-0421441-A2 | Pantothenic acid derivatives | FUJIREBIO INC. (JP) | 1991-04-10 | — | — | EP | disclosed |