Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | IDH1 | O75874 | 1/20 | 0.30 |
| ▸ | CDK9 | P50750 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20379045 | 0.83 | NPC1 (0.38) | NPC1RAB9ACA12CA9GRIN2B | |
| SCHEMBL30194787 | 0.83 | NPC1 (0.38) | NPC1RAB9ACA12CA9GRIN2B | |
| SCHEMBL25658526 | 0.81 | POLB (0.30) | — | |
| SCHEMBL29521944 | 0.81 | MEN1 (0.33) | NPSR1 | |
| SCHEMBL17941403 | 0.81 | MEN1 (0.33) | NPSR1 | |
| SCHEMBL20379039 | 0.80 | — | — | |
| SCHEMBL29574039 | 0.80 | — | — | |
| SCHEMBL20393693 | 0.79 | CYP11B1 (0.33) | NPC1RAB9ACA12CA9 | |
| SCHEMBL24175437 | 0.79 | — | — | |
| SCHEMBL19712018 | 0.79 | L3MBTL1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018130443-A1 | HETEROCYCLENE DERIVATIVES AS PEST CONTROL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2018-07-19 | — | — | WO | disclosed |