Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SDHB | P21912 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30194787 | 1.00 | NPC1 (0.38) | NPC1RAB9ACA12CA9PTGS2 | |
| SCHEMBL20393716 | 0.87 | NPC1 (0.52) | NPC1RAB9ACA12CA9PTGS2 | |
| SCHEMBL20393844 | 0.86 | NPC1 (0.36) | NPC1RAB9ACA12CA9PTGS2 | |
| SCHEMBL19366948 | 0.86 | GRIN2B (0.37) | NPC1RAB9ACA12CA9PTGS2 | |
| SCHEMBL20393627 | 0.84 | NPC1 (0.35) | NPC1RAB9ACA12CA9PTGS2 | |
| SCHEMBL20393710 | 0.84 | PTGS2 (0.42) | CA12CA9PTGS2KCNH2PTGS1 | |
| SCHEMBL20393708 | 0.84 | PTGS2 (0.40) | NPC1RAB9ACA12CA9PTGS2 | |
| SCHEMBL20393626 | 0.83 | PTGS2 (0.35) | NPC1RAB9APTGS2KCNH2GRIN2B | |
| SCHEMBL20393740 | 0.83 | NPC1 (0.32) | NPC1RAB9ACA12CA9GRIN2B | |
| SCHEMBL20393624 | 0.83 | KCNH2 (0.31) | NPC1RAB9AKCNH2CNR2S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110312718-B | Heterocyclene derivatives as pest control agents | 拜耳公司 | 2023-02-28 | — | — | CN | disclosed |
| US-11083199-B2 | Heterocycle derivatives as pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 2021-08-10 | — | — | US | disclosed |
| US-11083199-B2 | Heterocycle derivatives as pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 2021-08-10 | — | — | US | disclosed |
| US-20200045976-A1 | HETEROCYCLE DERIVATIVES AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-02-13 | — | — | US | disclosed |
| US-20200045976-A1 | HETEROCYCLE DERIVATIVES AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-02-13 | — | — | US | disclosed |
| EP-3568395-A1 | HETEROCYCLENE DERIVATIVES AS PEST CONTROL AGENTS | Bayer Aktiengesellschaft (DE) | 2019-11-20 | — | — | EP | disclosed |
| WO-2018130443-A1 | HETEROCYCLENE DERIVATIVES AS PEST CONTROL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2018-07-19 | — | — | WO | disclosed |
| WO-2018130443-A1 | HETEROCYCLENE DERIVATIVES AS PEST CONTROL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2018-07-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11083199-B2 | Heterocycle derivatives as pesticides | DDT, CBR3, CBR1 | NPC1 3182/4885RAB9A 892/4885CA12 3994/4885 |
| US-20200045976-A1 | HETEROCYCLE DERIVATIVES AS PESTICIDES | DDT, CBR3, CBR1 | NPC1 3182/4885RAB9A 892/4885CA12 3994/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.