SCHEMBL20394339

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20394498	0.83	ALDH1A1 (0.32)	ALDH1A1DRD1
	SCHEMBL20394248	0.83	BRD4 (0.37)	BRD4ALDH1A1CYP2C19DRD1CYP1A2
	SCHEMBL20394258	0.80	DRD1 (0.34)	ALDH1A1DRD1
	SCHEMBL18661513	0.79	PDE10A (0.42)	GPBAR1
	SCHEMBL18661454	0.78	PDE10A (0.35)	DRD1
	SCHEMBL20406568	0.77	DRD1 (0.38)	ALDH1A1DRD1
	SCHEMBL20394327	0.76	CYP17A1 (0.38)	DRD1CYP1A2
	SCHEMBL20394302	0.76	PDE10A (0.36)	—
	SCHEMBL20406756	0.76	BRD4 (0.43)	BRD4FFAR1BRD2CREBBPALDH1A1
	SCHEMBL18661516	0.75	PDE10A (0.45)	ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.