Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487323 | 0.93 | TSHR (0.62) | TSHRALDH1A1THRBADORA2AAPP | |
| SCHEMBL10405585 | 0.91 | ALDH1A1 (0.64) | TSHRALDH1A1 | |
| SCHEMBL17135313 | 0.88 | TSHR (0.56) | TSHRALDH1A1THRBADORA2AAPP | |
| SCHEMBL31186647 | 0.88 | TSHR (0.56) | TSHRALDH1A1THRBADORA2AAPP | |
| SCHEMBL29078238 | 0.88 | TSHR (0.56) | TSHRALDH1A1THRBADORA2AAPP | |
| SCHEMBL24506037 | 0.88 | TSHR (0.56) | TSHRALDH1A1THRBADORA2AAPP | |
| SCHEMBL4579700 | 0.83 | TSHR (0.68) | TSHRALDH1A1THRB | |
| SCHEMBL440643 | 0.82 | TSHR (0.58) | TSHRALDH1A1THRB | |
| SCHEMBL2675457 | 0.82 | TSHR (0.58) | TSHRALDH1A1THRB | |
| SCHEMBL20472550 | 0.81 | TSHR (0.56) | TSHRALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180208690-A1 | CURABLE COMPOSITION | TOAGOSEI CO., LTD. (JP) | 2018-07-26 | — | — | US | disclosed |