SCHEMBL20399474

SCHEMBL20399474

CCc1cc(OC)c(O)cc1Cc1cc(O)c(OC)cc1CC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HMGCR P04035 2/20 0.48
TAAR1 Q96RJ0 2/20 0.44
ALOX15 P16050 2/20 0.42
ALOX12 P18054 1/20 0.42
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
AKR1B1 P15121 1/20 0.42
CA7 P43166 1/20 0.42
MCL1 Q07820 1/20 0.42
CA9 Q16790 1/20 0.42
CA13 Q8N1Q1 1/20 0.42
KDM4E B2RXH2 3/20 0.41
MAPT P10636 3/20 0.41
CYP3A4 P08684 3/20 0.41
RECQL P46063 2/20 0.41
HPGD P15428 2/20 0.41
HSD17B2 P37059 1/20 0.41
LMNA P02545 1/20 0.41
HSD17B10 Q99714 1/20 0.41
MAOB P27338 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26664827 1.00 HMGCR (0.48) HMGCRTAAR1ALOX15ALOX12CA12
SCHEMBL13225464 0.85 TAAR1 (0.50) HMGCRTAAR1ALOX15ALOX12CA12
SCHEMBL26615249 0.85 HMGCR (0.65) HMGCRTAAR1KDM4EMAPTCYP3A4
SCHEMBL31317789 0.85 HMGCR (0.65) HMGCRTAAR1KDM4EMAPTCYP3A4
SCHEMBL20399527 0.85 HMGCR (0.65) HMGCRTAAR1KDM4EMAPTCYP3A4
SCHEMBL26110762 0.83 HMGCR (0.57) HMGCRTAAR1ALOX15CA12CA1
SCHEMBL7083643 0.82 ALDH1A1 (0.43) HMGCRTAAR1ALOX15ALOX12CA12
SCHEMBL14283818 0.81 HMGCR (0.53) HMGCRTAAR1ALOX15ALOX12KDM4E
SCHEMBL31490365 0.80 ALDH1A1 (0.53) HMGCRALOX15KDM4EMAPTCYP3A4
SCHEMBL27933598 0.80 ALDH1A1 (0.53) HMGCRALOX15KDM4EMAPTCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3571180-B1 PRODUCTION OF HIGHLY PURE META,META-COUPLED BIS(4-ALKYLPHENOL) DERIVATIVES AND USES THEREOF UNIV LEUVEN KATH (BE) 2024-12-18 EP disclosed
US-20210070684-A1 PRODUCTION OF HIGHLY PURE META,META-COUPLED BIS(4-ALKYLPHENOL) DERIVATIVES AND USES THEREOF KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2021-03-11 US disclosed
EP-3571180-A1 PRODUCTION OF HIGHLY PURE META,META-COUPLED BIS(4-ALKYLPHENOL) DERIVATIVES AND USES THEREOF Katholieke Universiteit Leuven (BE) 2019-11-27 EP disclosed
WO-2018134427-A1 PRODUCTION OF HIGHLY PURE META,META-COUPLED BIS(4-ALKYLPHENOL) DERIVATIVES AND USES THEREOF KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2018-07-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210070684-A1 PRODUCTION OF HIGHLY PURE META,META-COUPLED BIS(4-ALKYLPHENOL) DERIVATIVES AND USES THEREOF MMS19, PCBP1, PBRM1 HMGCR 1486/4885TAAR1 2746/4885ALOX15 408/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.