Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 9/20 | 0.36 |
| ▸ | KDM4A | O75164 | 8/20 | 0.36 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.36 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.34 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.32 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KDM5A | P29375 | 1/20 | 0.31 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25412574 | 0.83 | GGPS1 (0.41) | KDM4CKDM4APHF8KDM2ATP53 | |
| SCHEMBL30504568 | 0.81 | KDM4C (0.32) | KDM4CKDM4APHF8KDM2AFUT7 | |
| SCHEMBL611893 | 0.80 | ALDH1A1 (0.61) | ALDH1A1TSHRKDM4CKDM4APHF8 | |
| SCHEMBL612965 | 0.80 | ALDH1A1 (0.61) | ALDH1A1TSHRKDM4CKDM4APHF8 | |
| SCHEMBL614192 | 0.80 | ALDH1A1 (0.61) | ALDH1A1TSHRKDM4CKDM4APHF8 | |
| SCHEMBL23011936 | 0.80 | ALDH1A1 (0.61) | ALDH1A1TSHRKDM4CKDM4APHF8 | |
| SCHEMBL8411431 | 0.80 | ALDH1A1 (0.61) | ALDH1A1TSHRKDM4CKDM4APHF8 | |
| SCHEMBL613981 | 0.80 | ALDH1A1 (0.61) | ALDH1A1TSHRKDM4CKDM4APHF8 | |
| SCHEMBL11587394 | 0.80 | ALDH1A1 (0.61) | ALDH1A1TSHRKDM4CKDM4APHF8 | |
| SCHEMBL614348 | 0.80 | ALDH1A1 (0.61) | ALDH1A1TSHRKDM4CKDM4APHF8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2516511-A2 | THICKENER OR GELLANT FOR OIL MATERIALS, GEL COMPOSITION COMPRISING SAME, AND METHOD OF PRODUCING COSMETIC MATERIAL OR TOPICAL AGENT | Dow Corning Toray Co., Ltd. (JP) | 2012-10-31 | — | — | EP | disclosed |
| WO-2011078395-A2 | THICKENER OR GELLANT FOR OIL MATERIALS, GEL COMPOSITION COMPRISING SAME, AND METHOD OF PRODUCING COSMETIC MATERIAL OR TOPICAL AGENT | DOW CORNING TORAY CO., LTD. (JP) | 2011-06-30 | — | — | WO | disclosed |