SCHEMBL612965

SCHEMBL612965

CC(C)CCCCCCCN(C)C

nearest known ligand 0.61

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.61
TSHR P16473 1/20 0.61
DNM1 Q05193 3/20 0.50
LMNA P02545 1/20 0.46
KDM4C Q9H3R0 5/20 0.38
KDM4A O75164 4/20 0.38
PHF8 Q9UPP1 2/20 0.38
KDM2A Q9Y2K7 2/20 0.38
SIGMAR1 Q99720 2/20 0.37
HTR2A P28223 1/20 0.37
HRH1 P35367 1/20 0.37
LSS P48449 1/20 0.33
KDM5A P29375 1/20 0.32
KDM7A Q6ZMT4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1020960 1.00 ALDH1A1 (0.61) ALDH1A1TSHRDNM1LMNAKDM4C
SCHEMBL614192 1.00 ALDH1A1 (0.61) ALDH1A1TSHRDNM1LMNAKDM4C
SCHEMBL613011 1.00 ALDH1A1 (0.61) ALDH1A1TSHRDNM1LMNAKDM4C
SCHEMBL611893 1.00 ALDH1A1 (0.61) ALDH1A1TSHRDNM1LMNAKDM4C
SCHEMBL8411431 1.00 ALDH1A1 (0.61) ALDH1A1TSHRDNM1LMNAKDM4C
SCHEMBL614348 1.00 ALDH1A1 (0.61) ALDH1A1TSHRDNM1LMNAKDM4C
SCHEMBL23011936 1.00 ALDH1A1 (0.61) ALDH1A1TSHRDNM1LMNAKDM4C
SCHEMBL11587394 1.00 ALDH1A1 (0.61) ALDH1A1TSHRDNM1LMNAKDM4C
SCHEMBL613981 1.00 ALDH1A1 (0.61) ALDH1A1TSHRDNM1LMNAKDM4C
SCHEMBL18807938 1.00 ALDH1A1 (0.61) ALDH1A1TSHRDNM1LMNAKDM4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2421874-B1 COMPOSITION CONTAINING QUATERNARY AMINO-FUNCTIONAL ORGANOSILICON COMPOUNDS AND PRODUCTION AND USE THEREOF EVONIK DEGUSSA GMBH (DE) 2015-09-30 EP claimed
US-8979996-B2 Composition containing quaternary amino-functional organosilicon compunds and production and use thereof EVONIK DEGUSSA GMBH (DE) 2015-03-17 US claimed
US-20140208981-A1 COMPOSITION CONTAINING QUATERNARY AMINO-FUNCTIONAL ORGANOSILICON COMPOUNDS AND PRODUCTION AND USE THEREOF EVONIK DEGUSSA GMBH (DE) 2014-07-31 US claimed
US-8728225-B2 Composition containing quaternary amino-functional organosilicon compounds and production and use thereof EVONIK DEGUSSA GMBH (DE) 2014-05-20 US claimed
EP-2421874-A1 COMPOSITION CONTAINING QUATERNARY AMINO-FUNCTIONAL ORGANOSILICON COMPOUNDS AND PRODUCTION AND USE THEREOF Evonik Degussa GmbH (DE) 2012-02-29 EP claimed
US-20120037040-A1 COMPOSITION CONTAINING QUATERNARY AMINO-FUNCTIONAL ORGANOSILICON COMPOUNDS AND PRODUCTION AND USE THEREOF EVONIK DEGUSSA GMBH (DE) 2012-02-16 US claimed
WO-2010121873-A1 COMPOSITION CONTAINING QUATERNARY AMINO-FUNCTIONAL ORGANOSILICON COMPOUNDS AND PRODUCTION AND USE THEREOF EVONIK DEGUSSA GMBH (DE) 2010-10-28 WO claimed
WO-2024112876-A2 SPLIT SYNTHESIS OF LONG RNAS PRIME MEDICINE, INC. (US) 2024-05-30 WO disclosed
US-11827641-B2 Toll-like receptor antagonist compounds and methods of use DYNAVAX TECHNOLOGIES CORPORATION (US) 2023-11-28 US disclosed
EP-4194563-A1 TRANSPOSASE COMPETITOR CONTROL SYSTEM Kapa Biosystems, Inc. (US) 2023-06-14 EP disclosed
US-20230144292-A1 IRAK DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS, INC. 2023-05-11 US disclosed
CN-102405224-B Comprise composition and the Synthesis and applications thereof of season amino-functional silicoorganic compound EVONIK DEGUSSA GMBH (DE) 2015-12-16 CN disclosed
EP-2421874-B1 COMPOSITION CONTAINING QUATERNARY AMINO-FUNCTIONAL ORGANOSILICON COMPOUNDS AND PRODUCTION AND USE THEREOF EVONIK DEGUSSA GMBH (DE) 2015-09-30 EP disclosed
CN-102405263-A Dispersion containing silicon dioxide particles surface-modified with quaternized amino-functional organosilicon compounds EVONIK DEGUSSA GMBH 2012-04-04 CN disclosed
EP-2421874-A1 COMPOSITION CONTAINING QUATERNARY AMINO-FUNCTIONAL ORGANOSILICON COMPOUNDS AND PRODUCTION AND USE THEREOF Evonik Degussa GmbH (DE) 2012-02-29 EP disclosed
EP-2421921-A1 DISPERSION CONTAINING SILICA PARTICLES SURFACE-MODIFIED WITH QUATERNARY, AMINOFUNCTIONAL ORGANOSILICON COMPOUNDS Evonik Degussa GmbH (DE) 2012-02-29 EP disclosed
US-20120037040-A1 COMPOSITION CONTAINING QUATERNARY AMINO-FUNCTIONAL ORGANOSILICON COMPOUNDS AND PRODUCTION AND USE THEREOF EVONIK DEGUSSA GMBH (DE) 2012-02-16 US disclosed
US-20120006228-A1 DISPERSION CONTAINING SILICA PARTICLES SURFACE-MODIFIED WITH QUATERNARY, AMINOFUNCTIONAL ORGANOSILICON COMPOUNDS EVONIK DEGUSSA GMBH (DE) 2012-01-12 US disclosed
WO-2010121878-A1 DISPERSION CONTAINING SILICA PARTICLES SURFACE-MODIFIED WITH QUATERNARY, AMINOFUNCTIONAL ORGANOSILICON COMPOUNDS EVONIK DEGUSSA GMBH (DE) 2010-10-28 WO disclosed
WO-2010121873-A1 COMPOSITION CONTAINING QUATERNARY AMINO-FUNCTIONAL ORGANOSILICON COMPOUNDS AND PRODUCTION AND USE THEREOF EVONIK DEGUSSA GMBH (DE) 2010-10-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11827641-B2 Toll-like receptor antagonist compounds and methods of use TLR7, TLR9, TLR1 ALDH1A1 3948/4885TSHR 788/4885DNM1 2580/4885
US-20230144292-A1 IRAK DEGRADERS AND USES THEREOF IRAK2, IRAK3, IRAK1 ALDH1A1 2776/4885TSHR 3319/4885DNM1 4044/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.