Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.30 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2487994 | 0.83 | BRD4 (0.39) | NR1H2BRD4EPHX2 | |
| SCHEMBL6344069 | 0.80 | BRD4 (0.41) | NR1H2BRD4EPHX2 | |
| Hydrochloric Acid SCHEMBL28770722 | 0.78 | BRD4 (0.40) | NR1H2BRD4EPHX2 | |
| SCHEMBL15106713 | 0.72 | BRD4 (0.43) | NR1H2BRD4EPHX2CA12CA2 | |
| SCHEMBL1188680 | 0.71 | BRD4 (0.42) | BRD4EPHX2EPHX1 | |
| SCHEMBL19806324 | 0.70 | TSHR (0.41) | EPHX2 | |
| SCHEMBL12561079 | 0.69 | SCN9A (0.34) | BRD4EPHX2 | |
| SCHEMBL21144175 | 0.68 | — | — | |
| SCHEMBL29253020 | 0.68 | — | — | |
| SCHEMBL12206362 | 0.68 | ALDH1A1 (0.38) | EPHX2CA12CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2997032-B1 | 6-BRIDGED HETEROARYLDIHYDROPYRIMIDINES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | HOFFMANN LA ROCHE (CH) | 2018-07-25 | — | — | EP | disclosed |