Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | PRKCA | P17252 | 2/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.30 |
| ▸ | MGAM | O43451 | 1/20 | 0.30 |
| ▸ | SI | P14410 | 1/20 | 0.30 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6344069 | 0.89 | BRD4 (0.41) | BRD4NR1H2HSD17B10CYP3A4MAPT | |
| Hydrochloric Acid SCHEMBL28770722 | 0.87 | BRD4 (0.40) | BRD4NR1H2HSD17B10CYP3A4MAPT | |
| SCHEMBL15106713 | 0.85 | BRD4 (0.43) | BRD4NR1H2HSD17B10CYP3A4MAPT | |
| SCHEMBL20403281 | 0.83 | NR1H2 (0.36) | BRD4NR1H2EPHX2 | |
| SCHEMBL12206362 | 0.83 | ALDH1A1 (0.38) | HSD17B10APLNRTSHRGAAEPHX2 | |
| SCHEMBL51471 | 0.79 | BRD4 (0.39) | BRD4NR1H2HSD17B10TSHRGAA | |
| SCHEMBL12561079 | 0.77 | SCN9A (0.34) | BRD4SCN9ATSHRGAANAAA | |
| SCHEMBL29224201 | 0.77 | SLC6A1 (0.39) | MAPTAPLNR | |
| SCHEMBL3185201 | 0.77 | SLC6A1 (0.39) | MAPTAPLNR | |
| SCHEMBL29067928 | 0.76 | BRD4 (0.37) | BRD4NR1H2APLNRTSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102712577-B | Substituted 3-phenylpropionic acids and the use thereof | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-10-15 | — | — | CN | disclosed |
| CN-103796989-A | Branched 3-phenylpropionic acid derivatives and uses thereof | BAYER IP GMBH | 2014-05-14 | — | — | CN | disclosed |
| CN-103492361-A | Substituted 1-benzylcycloalkylcarboxlic acids and use thereof | BAYER IP GMBH | 2014-01-01 | — | — | CN | disclosed |
| CN-102712577-A | Substituted 3-phenylpropionic acids and the use thereof | BAYER SCHERING PHARMA AG | 2012-10-03 | — | — | CN | disclosed |
| EP-1697311-B1 | NITRILE COMPOUND AND ITS USE IN PEST CONTROL | SUMITOMO CHEMICAL CO (JP) | 2011-10-26 | — | — | EP | disclosed |
| US-7662402-B2 | contains fluoroalkyl group; insecticides, miticides, nematocides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-02-16 | — | — | US | disclosed |
| US-7662402-B2 | contains fluoroalkyl group; insecticides, miticides, nematocides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-02-16 | — | — | US | disclosed |
| US-7662402-B2 | contains fluoroalkyl group; insecticides, miticides, nematocides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-02-16 | — | — | US | disclosed |
| CN-100390140-C | Nitrile compounds and their use in pest control | SUMITOMO CHEMICAL CO (JP) | 2008-05-28 | — | — | CN | disclosed |
| US-20070112068-A1 | Nitrile compound and its use in pest control | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-05-17 | — | — | US | disclosed |
| US-20070112068-A1 | Nitrile compound and its use in pest control | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-05-17 | — | — | US | disclosed |
| US-20070112068-A1 | Nitrile compound and its use in pest control | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-05-17 | — | — | US | disclosed |
| CN-1898200-A | Nitrile compound and its pest control use | SUMITOMO CHEMICAL CO (JP) | 2007-01-17 | — | — | CN | disclosed |
| EP-1697311-A1 | NITRILE COMPOUND AND ITS USE IN PEST CONTROL | Sumitomo Chemical Company, Limited (JP) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005063694-A1 | NITRILE COMPOUND AND ITS USE IN PEST CONTROL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-07-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070112068-A1 | Nitrile compound and its use in pest control | C5, C9, C1S | BRD4 1585/4885NR1H2 2160/4885HSD17B10 2825/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.