Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Salicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.64 |
| ▸ | HPGD | P15428 | 6/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.64 |
| ▸ | CA1 | P00915 | 2/20 | 0.64 |
| ▸ | CA9 | Q16790 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | CA12 | O43570 | 1/20 | 0.64 |
| ▸ | CA2 | P00918 | 1/20 | 0.64 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.64 |
| ▸ | CA4 | P22748 | 1/20 | 0.64 |
| ▸ | CA6 | P23280 | 1/20 | 0.64 |
| ▸ | CA7 | P43166 | 1/20 | 0.64 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.64 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | G6PD | P11413 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phthalic Acid SCHEMBL35170 | 0.89 | ALDH1A1 (0.58) | ALDH1A1HPGDKDM4ECA1CA9 | |
| Salicylic Acid SCHEMBL28514493 | 0.84 | HPGD (0.67) | ALDH1A1HPGDKDM4ECA1CA9 | |
| Salicylic Acid SCHEMBL5943083 | 0.83 | ALDH1A1 (0.56) | ALDH1A1HPGDKDM4ECA1CA9 | |
| Salicylic Acid SCHEMBL2987530 | 0.83 | ALDH1A1 (0.78) | ALDH1A1HPGDKDM4ECA1CA9 | |
| Salicylic Acid SCHEMBL11396302 | 0.81 | HPGD (0.75) | ALDH1A1HPGDKDM4ECA1CA9 | |
| Salicylic Acid SCHEMBL31534584 | 0.81 | ALDH1A1 (0.75) | ALDH1A1HPGDKDM4ECA1CA9 | |
| Salicylic Acid SCHEMBL28128382 | 0.81 | ALDH1A1 (0.75) | ALDH1A1HPGDKDM4ECA1CA9 | |
| Salicylic Acid SCHEMBL3999097 | 0.81 | ALDH1A1 (0.62) | ALDH1A1HPGDKDM4ECA1CA9 | |
| Salicylic Acid SCHEMBL10760465 | 0.80 | ALDH1A1 (0.90) | ALDH1A1HPGDKDM4ECA1CA9 | |
| Salicylic Acid SCHEMBL11780863 | 0.80 | ALDH1A1 (0.90) | ALDH1A1HPGDKDM4ECA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7960324-B2 | Additive composition having low temperature viscosity corrosion and detergent properties | CHEVRON ORONITE COMPANY LLC (US) | 2011-06-14 | — | — | US | disclosed |