Phthalic Acid

Phthalic Acid

SCHEMBL35170

C=CCC(=O)O.O=C(O)c1ccccc1C(=O)O

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.58
ALOX15 P16050 1/20 0.58
KMT2A Q03164 2/20 0.49
AKR1C3 P42330 1/20 0.47
CYP3A4 P08684 1/20 0.46
NR4A1 P22736 1/20 0.45
NR4A2 P43354 1/20 0.45
NR4A3 Q92570 1/20 0.45
KDM4E B2RXH2 1/20 0.45
CA12 O43570 1/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
HMGB1 P09429 1/20 0.45
HPGD P15428 1/20 0.45
CA4 P22748 1/20 0.45
CA6 P23280 1/20 0.45
CA7 P43166 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
CA9 Q16790 1/20 0.45
NAPRT Q6XQN6 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phthalic Acid SCHEMBL1325027 0.89 ALDH1A1 (0.47) ALDH1A1ALOX15KMT2AAKR1C3CYP3A4
Salicylic Acid SCHEMBL2040340 0.89 ALDH1A1 (0.64) ALDH1A1ALOX15KMT2ACYP3A4KDM4E
Phthalic Acid SCHEMBL7201091 0.87 ALDH1A1 (0.44) ALDH1A1ALOX15KMT2AAKR1C3CYP3A4
Benzoic Acid SCHEMBL11147183 0.83 TSHR (0.58) ALDH1A1ALOX15KMT2ACYP3A4NR4A2
Biphenyl SCHEMBL11045970 0.83 LMNA (0.48) ALDH1A1KMT2AKDM4EHPGDSMN1; SMN2
Phthalic Acid SCHEMBL23929048 0.83 ALDH1A1 (0.64) ALDH1A1ALOX15KMT2AAKR1C3CYP3A4
Phthalic Acid SCHEMBL21332399 0.83 ALDH1A1 (0.64) ALDH1A1ALOX15KMT2AAKR1C3CYP3A4
Benzene SCHEMBL11645295 0.82 ALDH1A1 (0.47) ALDH1A1ALOX15KMT2ACYP3A4HPGD
Phthalic Acid SCHEMBL28549489 0.81 ALDH1A1 (0.61) ALDH1A1ALOX15KMT2AAKR1C3CYP3A4
Phenol SCHEMBL17183829 0.81 CA2 (0.48) ALDH1A1CYP3A4CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 8677 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3925601-B1 GASTRO-RESISTANT FORMULATION CONTAINING POSACONAZOLE AND A POLYMERIC PRECIPITATION INHIBITOR TIEFENBACHER ALFRED E GMBH & CO KG (DE) 2024-07-17 EP claimed
US-20240173284-A1 EFLORNITHINE AND SULINDAC, FIXED DOSE COMBINATION FORMULATION CANCER PREVENTION PHARMACEUTICALS, INC. (US) 2024-05-30 US claimed
US-20240100122-A1 FORMULATIONS Sublimity Therapeutics Limited (IE) 2024-03-28 US claimed
US-20240091304-A1 FORMULATIONS COMPRISING CYCLOSPORIN A Sublimity Therapeutics Limited (IE) 2024-03-21 US claimed
EP-3065721-B1 FORMULATIONS COMPRISING CYCLOSPORIN A SUBLIMITY THERAPEUTICS LTD (IE) 2024-03-13 EP claimed
EP-3065716-B1 FORMULATIONS SUBLIMITY THERAPEUTICS LTD (IE) 2023-12-20 EP claimed
EP-3137060-B2 EXTENDED RELEASE SUSPENSION COMPOSITIONS SUN PHARMACEUTICAL IND LTD (IN) 2023-12-20 EP claimed
WO-2023204397-A1 PHARMACEUTICAL COMPOSITION COMPRISING ACETYLSALICYLIC ACID AND PROTON PUMP INHIBITOR 한미약품 주식회사 2023-10-26 WO claimed
WO-2023154805-A2 DRY FORMULATED NITROGEN-FIXING MICROBE PACKAGED IN WATER-SOLUBLE FILM FOR RAPID AND SAFE DISPERSAL IN AQUEOUS MIXTURES PIVOT BIO, INC. (US) 2023-08-17 WO claimed
US-11707550-B2 Polyphosphate-functionalized inorganic nanoparticles as hemostatic compositions and methods of use THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-07-25 US claimed
WO-1985003436-A1 DIFFUSION COATED MULTIPLE-UNITS DOSAGE FORM A/S ALFRED BENZON (DK) 1985-08-15 WO claimed
WO-1985001207-A1 ENTERIC FILM-COATING COMPOSITIONS COLORCON, INC. (US) 1985-03-28 WO claimed
US-4482386-A Method of conditioning a water swellable hydrocolloid WARNER-LAMBERT COMPANY (US) 1984-11-13 US claimed
EP-0118240-A2 Process for injection moulding starch WARNER-LAMBERT COMPANY (US) 1984-09-12 EP claimed
EP-0092908-A2 Hydrophilic polymer composition for injection molding WARNER-LAMBERT COMPANY (US) 1983-11-02 EP claimed
US-4377568-A Preparation of aqueous alcoholic dispersions of pH sensitive polymers and plasticizing agents and a method of enteric coating dosage forms using same MERCK SHARP & DOHME (I.A.) CORP. (CA) 1983-03-22 US claimed
EP-0072021-A2 Aqueous alcoholic dispersions of pH sensitive polymers and plasticizing agents, a process for preparing the same, and a solid medicinal oral dosage form containing an enteric coating prepared by using same MERCK SHARP & DOHME (I.A.) CORP. (US) 1983-02-16 EP claimed
US-4248857-A PROPRANOLOL AND SUGAR COATING ON A CORE OF PROPRANOLOL, POLYACRYLIC ACID, STEARIC ACID AND MANNITOL; ENERGIC BLOCKING AGENT AMERICAN HOME PRODUCTS CORPORATION (US) 1981-02-03 US claimed
US-4248858-A COMPRISING A CORE OF PROPRANOLOL, A CELLULOSE DERIVATIVE AND ETHYL CELLULOSE, AN ENTERIC COATING AND A SUGAR COATING CONTAINING PROPRANOLOL AMERICAN HOME PRODUCTS CORPORATION (US) 1981-02-03 US claimed
US-4248856-A COMPRISING A CELLULOSIC CORE, SUGAR COATING AND HAVING PROPRANOLOL IN BOTH AMERICAN HOME PRODUCTS CORPORATION (US) 1981-02-03 US claimed