Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | FDPS | P14324 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | GLS | O94925 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18338554 | 0.78 | HTT (0.40) | HTTFDPSTSHRTDP1HDAC1 | |
| SCHEMBL27726715 | 0.75 | HTT (0.38) | HTTFDPSTSHRTDP1HDAC1 | |
| SCHEMBL16861331 | 0.72 | FDPS (0.36) | FDPSTSHRTDP1CA12CA1 | |
| SCHEMBL30171197 | 0.71 | AR (0.46) | HTTFDPSTSHRTDP1HDAC1 | |
| SCHEMBL27726640 | 0.70 | FDPS (0.37) | HTTFDPSTSHRTDP1HDAC1 | |
| SCHEMBL1073206 | 0.70 | — | — | |
| SCHEMBL7838436 | 0.69 | TSHR (0.41) | HTTFDPSTSHRTDP1HDAC1 | |
| Trifluoroacetic Acid SCHEMBL29488711 | 0.69 | HTT (0.39) | HTTFDPSTSHRTDP1HDAC1 | |
| SCHEMBL14744196 | 0.68 | AR (0.36) | HTTFDPSTSHRTDP1HDAC1 | |
| Bromide SCHEMBL6981267 | 0.68 | FDPS (0.44) | HTTFDPSTSHRTDP1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970388-B1 | PEPTIDE COMPOSITIONS | RHYTHM PHARMACEUTICALS INC (US) | 2018-07-25 | — | — | EP | disclosed |