Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | FBP1 | P09467 | 1/20 | 0.38 |
| ▸ | GRK6 | P43250 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | DYRK3 | O43781 | 2/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.35 |
| ▸ | DYRK2 | Q92630 | 2/20 | 0.35 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2040560 | 1.00 | KDM4E (0.45) | KDM4ESMN1; SMN2ALDH1A1CYP2A6HSP90AA1 | |
| SCHEMBL1609841 | 0.81 | KDM4E (0.64) | KDM4ESMN1; SMN2ALDH1A1CYP2A6HSP90AA1 | |
| SCHEMBL1609843 | 0.81 | KDM4E (0.64) | KDM4ESMN1; SMN2ALDH1A1CYP2A6HSP90AA1 | |
| SCHEMBL31402276 | 0.80 | SMN1; SMN2 (0.49) | KDM4ESMN1; SMN2ALDH1A1CYP2A6HSP90AA1 | |
| SCHEMBL2039106 | 0.80 | ALDH1A1 (0.67) | KDM4ESMN1; SMN2ALDH1A1CYP2A6HSP90AA1 | |
| SCHEMBL29450010 | 0.80 | ALDH1A1 (0.67) | KDM4ESMN1; SMN2ALDH1A1CYP2A6HSP90AA1 | |
| SCHEMBL11926858 | 0.78 | CYP2A6 (0.62) | KDM4ESMN1; SMN2ALDH1A1CYP2A6CHRNA7 | |
| SCHEMBL4820875 | 0.77 | SMN1; SMN2 (0.46) | KDM4ESMN1; SMN2ALDH1A1CYP2A6HSP90AA1 | |
| SCHEMBL1609796 | 0.76 | ALDH1A1 (0.41) | KDM4ESMN1; SMN2ALDH1A1HSP90AA1MAPT | |
| SCHEMBL1609795 | 0.76 | ALDH1A1 (0.41) | KDM4ESMN1; SMN2ALDH1A1HSP90AA1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120291159-A1 | Azoline Compounds for Combating Invertebrate Pests | BASF SE (DE) | 2012-11-15 | — | — | US | disclosed |
| WO-2011073444-A2 | AZOLINE COMPOUNDS FOR COMBATING INVERTEBRATE PESTS | BASF SE (DE) | 2011-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120291159-A1 | Azoline Compounds for Combating Invertebrate Pests | CRY1, PIR, DDT | KDM4E 576/4885SMN1; SMN2 2645/4885ALDH1A1 2327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.