Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 6/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.36 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.36 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.36 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20406170 | 0.89 | PDE10A (0.39) | PDE10AALDH1A1MAPTATMDRD1 | |
| SCHEMBL20394463 | 0.88 | PDE10A (0.38) | PDE10ASCN9APLAAT3PLAAT5PLAAT2 | |
| SCHEMBL20406169 | 0.85 | PDE10A (0.39) | PDE10ASCN9AALDH1A1MAPTATM | |
| SCHEMBL20406192 | 0.84 | PDE10A (0.41) | PDE10ASCN9ATRPV4ALDH1A1MAPT | |
| SCHEMBL20406280 | 0.83 | PDE10A (0.40) | PDE10AALDH1A1MAPTATMDRD1 | |
| SCHEMBL20406073 | 0.83 | PDE10A (0.35) | PDE10ASCN9ADRD1 | |
| SCHEMBL31474516 | 0.82 | GRM5 (0.42) | SCN9ATRPV4ALDH1A1MAPTGRM5 | |
| SCHEMBL26109314 | 0.82 | GRM5 (0.42) | SCN9ATRPV4ALDH1A1MAPTGRM5 | |
| SCHEMBL20406219 | 0.81 | PDE10A (0.46) | PDE10AALDH1A1MAPTATM | |
| SCHEMBL20406071 | 0.80 | PDE10A (0.44) | PDE10ADRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3351533-A1 | BIARYL DERIVATIVE AND MEDICINE CONTAINING SAME | Kaken Pharmaceutical Co., Ltd. (JP) | 2018-07-25 | — | — | EP | disclosed |