Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20406324 | 0.89 | PDE10A (0.38) | PDE10AALDH1A1MAPTATMDRD1 | |
| SCHEMBL20406227 | 0.83 | PDE10A (0.40) | PDE10AALDH1A1MAPTATMDRD1 | |
| SCHEMBL26107379 | 0.83 | RAB9A (0.41) | PDE10AALDH1A1MAPTATMDRD1 | |
| SCHEMBL30592014 | 0.83 | RAB9A (0.41) | PDE10AALDH1A1MAPTATMDRD1 | |
| SCHEMBL20406219 | 0.82 | PDE10A (0.46) | PDE10AALDH1A1MAPTATM | |
| SCHEMBL20406079 | 0.80 | PDE10A (0.44) | PDE10ADRD1RAB9AMEN1KMT2A | |
| SCHEMBL20406294 | 0.80 | FEN1 (0.42) | PDE10AALDH1A1MAPTDRD1RAB9A | |
| SCHEMBL20406233 | 0.80 | DRD1 (0.45) | PDE10ADRD1KMT2A | |
| SCHEMBL20406170 | 0.78 | PDE10A (0.39) | PDE10AALDH1A1MAPTATMDRD1 | |
| SCHEMBL4008297 | 0.77 | PDE10A (0.45) | PDE10AALDH1A1MAPTATMDRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3351533-A1 | BIARYL DERIVATIVE AND MEDICINE CONTAINING SAME | Kaken Pharmaceutical Co., Ltd. (JP) | 2018-07-25 | — | — | EP | disclosed |