Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | GCK | P35557 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20406227 | 0.85 | PDE10A (0.40) | PDE10ASCN9ADRD1ALDH1A1MAPT | |
| SCHEMBL20406073 | 0.85 | PDE10A (0.35) | PDE10AMEN1KMT2ASCN9ADRD1 | |
| SCHEMBL20406586 | 0.85 | MEN1 (0.37) | MEN1KMT2ASCN9AALDH1A1MAPT | |
| SCHEMBL20406293 | 0.83 | PDE10A (0.44) | PDE10AMEN1KMT2ASCN9ADRD1 | |
| SCHEMBL20406170 | 0.83 | PDE10A (0.39) | PDE10AMEN1KMT2ADRD1GCK | |
| SCHEMBL20406664 | 0.82 | CSF1R (0.34) | SCN9A | |
| SCHEMBL20394297 | 0.81 | ABL1 (0.41) | PDE10AMEN1KMT2A | |
| SCHEMBL20394448 | 0.78 | PDE10A (0.45) | PDE10AALDH1A1MAPT | |
| SCHEMBL20406475 | 0.78 | KMT2A (0.40) | PDE10AMEN1KMT2AMAPT | |
| SCHEMBL20406074 | 0.78 | PDE10A (0.39) | PDE10AMEN1KMT2ADRD1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3351533-A1 | BIARYL DERIVATIVE AND MEDICINE CONTAINING SAME | Kaken Pharmaceutical Co., Ltd. (JP) | 2018-07-25 | — | — | EP | disclosed |