Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 6/20 | 0.45 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 6/20 | 0.36 |
| ▸ | GCK | P35557 | 1/20 | 0.35 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20406059 | 0.83 | DRD1 (0.48) | DRD1KMT2APDE10AGCK | |
| SCHEMBL20406060 | 0.82 | DRD1 (0.41) | DRD1PDE10A | |
| SCHEMBL20406667 | 0.82 | DRD1 (0.42) | DRD1PPP1CAKMT2APDE10A | |
| SCHEMBL20406061 | 0.81 | DRD1 (0.45) | DRD1PDE10AGCK | |
| SCHEMBL20406280 | 0.80 | PDE10A (0.40) | DRD1KMT2APDE10A | |
| SCHEMBL20406574 | 0.79 | DRD1 (0.40) | DRD1PDE10A | |
| SCHEMBL20406390 | 0.78 | DRD1 (0.45) | DRD1KMT2APDE10AGCK | |
| SCHEMBL18661464 | 0.78 | KMT2A (0.43) | DRD1PPP1CAKMT2APDE10AP2RY1 | |
| SCHEMBL20406258 | 0.77 | DRD1 (0.56) | DRD1KMT2APDE10AGCK | |
| SCHEMBL20406227 | 0.76 | PDE10A (0.40) | DRD1PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3351533-A1 | BIARYL DERIVATIVE AND MEDICINE CONTAINING SAME | Kaken Pharmaceutical Co., Ltd. (JP) | 2018-07-25 | — | — | EP | disclosed |