Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20755006 | 0.86 | HDAC1 (0.34) | SCN9ASCN10A | |
| SCHEMBL20755016 | 0.83 | TRPV4 (0.39) | SCN9ASCN10A | |
| SCHEMBL20394479 | 0.78 | ABL1 (0.37) | — | |
| SCHEMBL20754954 | 0.76 | SCN9A (0.33) | SCN9ASCN10A | |
| SCHEMBL20754998 | 0.76 | CYP17A1 (0.36) | SCN9A | |
| SCHEMBL20406073 | 0.73 | PDE10A (0.35) | SCN9ASCN10A | |
| SCHEMBL20394303 | 0.72 | PDE10A (0.40) | — | |
| SCHEMBL20406228 | 0.72 | EGFR (0.42) | SCN9A | |
| SCHEMBL20406664 | 0.70 | CSF1R (0.34) | SCN9A | |
| SCHEMBL20406096 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3351533-A1 | BIARYL DERIVATIVE AND MEDICINE CONTAINING SAME | Kaken Pharmaceutical Co., Ltd. (JP) | 2018-07-25 | — | — | EP | disclosed |