Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20406318 | 0.84 | ICAM1 (0.38) | SCN9A | |
| SCHEMBL20406662 | 0.83 | TRPA1 (0.33) | CSF1RSCN9A | |
| SCHEMBL20406169 | 0.82 | PDE10A (0.39) | SCN9A | |
| SCHEMBL20406320 | 0.74 | EGFR (0.32) | — | |
| SCHEMBL20406586 | 0.72 | MEN1 (0.37) | SCN9A | |
| SCHEMBL20406321 | 0.71 | ALDH1A1 (0.36) | CSF1R | |
| SCHEMBL31395363 | 0.71 | TRPA1 (0.49) | — | |
| SCHEMBL17583157 | 0.71 | GRIN2B (0.40) | SCN9AGRIN2B | |
| SCHEMBL20755006 | 0.71 | HDAC1 (0.34) | SCN9A | |
| SCHEMBL20406282 | 0.70 | SCN9A (0.31) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3351533-A1 | BIARYL DERIVATIVE AND MEDICINE CONTAINING SAME | Kaken Pharmaceutical Co., Ltd. (JP) | 2018-07-25 | — | — | EP | disclosed |