Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | VDR | P11473 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CCR9 | P51686 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20406378 | 0.86 | PDE10A (0.46) | TDP1L3MBTL1ADRB2ADRB1MAPT | |
| SCHEMBL20394343 | 0.85 | PDE10A (0.48) | TDP1ADRB2ADRB1VDR | |
| SCHEMBL26177275 | 0.79 | GAA (0.50) | ALDH1A1TDP1L3MBTL1HTTNPSR1 | |
| SCHEMBL20394385 | 0.78 | PDE10A (0.54) | KMT2AVDRMAPT | |
| SCHEMBL20406488 | 0.78 | KMT2A (0.59) | ALDH1A1TDP1L3MBTL1HTTNPSR1 | |
| SCHEMBL4654749 | 0.76 | FFAR1 (0.70) | TDP1KMT2A | |
| SCHEMBL1745415 | 0.75 | FFAR1 (0.64) | VDR | |
| SCHEMBL2306572 | 0.73 | ITGB3 (0.48) | ALDH1A1TDP1L3MBTL1HTTNPSR1 | |
| SCHEMBL2306563 | 0.73 | ITGB3 (0.48) | ALDH1A1TDP1L3MBTL1HTTNPSR1 | |
| SCHEMBL20406614 | 0.73 | FFAR1 (0.54) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3351533-A1 | BIARYL DERIVATIVE AND MEDICINE CONTAINING SAME | Kaken Pharmaceutical Co., Ltd. (JP) | 2018-07-25 | — | — | EP | disclosed |