Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20406605 | 0.87 | LMNA (0.49) | PDE10ATDP1MAPTL3MBTL1 | |
| SCHEMBL20406366 | 0.86 | ALDH1A1 (0.46) | TDP1ADRB2ADRB1MAPTL3MBTL1 | |
| SCHEMBL20394343 | 0.84 | PDE10A (0.48) | PDE10ATDP1ADRB2ADRB1 | |
| SCHEMBL20406254 | 0.80 | PDE10A (0.46) | PDE10AMAPTL3MBTL1 | |
| SCHEMBL20406212 | 0.80 | PDE10A (0.43) | PDE10AMAPTL3MBTL1 | |
| SCHEMBL20406369 | 0.78 | LTA4H (0.47) | PDE10AMAPTL3MBTL1 | |
| SCHEMBL13331058 | 0.78 | PDE10A (0.56) | PDE10ATDP1MAPTL3MBTL1 | |
| SCHEMBL20394385 | 0.77 | PDE10A (0.54) | PDE10AMAPT | |
| SCHEMBL20406089 | 0.77 | L3MBTL1 (0.49) | PDE10ATDP1MAPTL3MBTL1 | |
| SCHEMBL17028531 | 0.77 | FFAR1 (0.52) | ADRB2ADRB1FFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3351533-A1 | BIARYL DERIVATIVE AND MEDICINE CONTAINING SAME | Kaken Pharmaceutical Co., Ltd. (JP) | 2018-07-25 | — | — | EP | disclosed |