Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20406230 | 0.92 | MEN1 (0.37) | MEN1KMT2AMAPTPDE10A | |
| SCHEMBL20406654 | 0.88 | RORC (0.44) | MEN1KMT2AMAPTPDE10A | |
| SCHEMBL20394208 | 0.83 | PDE10A (0.49) | AHRPDE10A | |
| SCHEMBL18661458 | 0.78 | PDE10A (0.52) | AHRMEN1KMT2APDE10A | |
| SCHEMBL18661463 | 0.76 | KDR (0.42) | PDE10A | |
| SCHEMBL20394312 | 0.76 | GPBAR1 (0.43) | PDE10A | |
| SCHEMBL18661536 | 0.76 | AHR (0.45) | AHRPDE10A | |
| SCHEMBL20406598 | 0.75 | PDE10A (0.43) | AHRMEN1KMT2APDE10A | |
| SCHEMBL25340568 | 0.75 | PDE10A (0.43) | ALDH1A1MAPTATMPDE10A | |
| SCHEMBL20394336 | 0.75 | FLT3 (0.41) | AHRPDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3351533-A1 | BIARYL DERIVATIVE AND MEDICINE CONTAINING SAME | Kaken Pharmaceutical Co., Ltd. (JP) | 2018-07-25 | — | — | EP | disclosed |