Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 4/20 | 0.35 |
| ▸ | FEN1 | P39748 | 2/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20406375 | 0.79 | P2RY1 (0.39) | P2RY1RORCDRD1 | |
| SCHEMBL20406442 | 0.79 | RORC (0.32) | P2RY1RORCDRD1 | |
| SCHEMBL20406590 | 0.77 | FEN1 (0.37) | FEN1RORC | |
| SCHEMBL20406779 | 0.76 | KMT2A (0.35) | FEN1 | |
| SCHEMBL20406717 | 0.76 | SYK (0.37) | — | |
| SCHEMBL20406475 | 0.76 | KMT2A (0.40) | P2RY1RORC | |
| SCHEMBL18661468 | 0.76 | SYK (0.39) | FEN1 | |
| SCHEMBL20394474 | 0.76 | SYK (0.41) | — | |
| SCHEMBL20394367 | 0.75 | SYK (0.38) | — | |
| SCHEMBL18661502 | 0.75 | PDE10A (0.39) | RORCDRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3351533-A1 | BIARYL DERIVATIVE AND MEDICINE CONTAINING SAME | Kaken Pharmaceutical Co., Ltd. (JP) | 2018-07-25 | — | — | EP | disclosed |